Pioneering a New Era of Neuroregeneration
As the first company to demonstrate in vivo nerve regeneration via 5-HT2A modulation, we are advancing precision agonists to restore neural circuitry and immune balance.
Why 2A Biosciences?
Restoring Native
Biology
Our assets activate intrinsic regenerative pathways to restore the body’s own capacity to repair, maintain, and resist degeneration.
Precision Pharmacology
Designed to enhance desired outcomes (i.e., regenerative, anti-inflammatory) without the hallucinogenic effects and off-target liabilities of typical 5-HT2A agonists.
One Platform,
Many Diseases
Neuroregeneration proven in ophthalmology enables expansion into CNS diseases via shared regenerative mechanisms.
Our lead program is rapidly advancing toward Phase 2a trials.
Peer-Reviewed Foundational Science
Serotonin, Immune Function, and Psychedelics as Potent Anti-Inflammatories
Charles D. Nichols, Timothy P. Foster
From Psychiatry to Neurology: Psychedelics as Prospective Therapeutics for Neurodegenerative Disorders
Urszula Kozlowska, Charles D. Nichols, Kalina Wiatr, Maciej Figiel
Psychedelics and Anti-Inflammatory Activity in Animal Models
Thomas W. Flanagan, Charles D. Nichols
5-HT2A Receptors: Pharmacology and Functional Selectivity
Benjamin R. Cummins, Gerald B. Billac, David E. Nichols, Charles D. Nichols
History of Psychedelic Drug Science and Molecular Pharmacology
David E. Nichols, Charles D. Nichols
